Hull FC travel to Southern France to take on Catalans Dragons and looking to cement their place in Super League's top four.
Peter Gentle's men have won nine of their last ten games, including an impressive victory over current champions Leeds last week.
Catalans slipped up at the weekend as they let Widnes claw back a late draw but they could force their way back into the top four with a win against Hull.
Scott Dureau makes the Catalans squad despite having to go to hospital after the Dragons' draw with Widnes. Lopini Paea and Damien Blanch return to Laurent Frayssinous' 19 but Brent Webb, Olivier Elima, Louis Anderson, Julian Bousquet and Jason Baitieri all remain sidelined.
The Black and Whites will travel to Perpignan looking for their tenth win in their last eleven matches but they must do without England winger Briscoe who has not made the trip to Perpignan due to a rib injury.
Former Australia and New South Wales prop O'Meley has also been ruled out with a minor hamstring injury picked up in his side's impressive 18-6 victory over defending champions Leeds Rhinos on Friday.
However, there is better news for forward Chris Green who is fit to play after receiving the all clear on a bicep injury, while winger Jason Crookes and centre Joe Arundel are drafted into Gentle's 19-man squad for the game..
Catalans Dragons 19-man squad: Blanch, Pryce, Taia, Bosc, Dureau, Henderson, Casty, Menzies, Mounis, Maria, Pelissier, Larroyer, Millard, Simon, Fakir, Paea, Duport, Vaccari, Escare.
Hull FC 19-man squad: Arundel, Bowden, Crookes, Crooks, Ellis, Galea, Green, Holdsworth, Heremaia, Houghton, Johnson, Lineham, Lynch, McDonnell, Pitts, Watts, Westerman, Whiting, Yeaman.