Wigan Warriors head coach Shaun Wane has brought in prop Callum Field and full-back Craig Mullen as cover for Tommy Leuluai and Oliver Partington for the clash with Hull FC
Kiwi hooker Leuluai is out with a groin problem, while front-rower Partington serves a one-game suspension.
Hull FC have an opportunity to avoid an 11th straight defeat, against a Wigan side unbeaten in the Super 8s.
Dean Hadley and Hakim Miloudi miss out through injury, with Cameron Scott and Jack Downs added to the squad.
Wigan, who will see Wane move on at the end of the season, have a home semi-final against Castleford to come on the back of this game and are already guaranteed a second-placed finish.
Their last league defeat came against rivals St Helens on the 19 July, with seven straight victories since.
Wigan (from): Bateman, Clubb, Davies, Escare, Field, Flower, Gildart, Greenwood, Hamlin, Manfredi, Mullen, Navarrete, Powell, Sarginson, Sutton, Tautai, Tomkins, Williams, Woods.
Hull FC (from): Shaul, Faraimo, Tuimavave, Griffin, Talanoa, Taylor, Houghton, Connor, Abdull, Washbrook, Fash, Litten, Paea, Lane, Downs, Matongo, Scott, Harris, Bienek.
Hull FC have an opportunity to avoid an 11th straight defeat, against a Wigan side unbeaten in the Super 8s.
Dean Hadley and Hakim Miloudi miss out through injury, with Cameron Scott and Jack Downs added to the squad.
Wigan, who will see Wane move on at the end of the season, have a home semi-final against Castleford to come on the back of this game and are already guaranteed a second-placed finish.
Their last league defeat came against rivals St Helens on the 19 July, with seven straight victories since.
Wigan (from): Bateman, Clubb, Davies, Escare, Field, Flower, Gildart, Greenwood, Hamlin, Manfredi, Mullen, Navarrete, Powell, Sarginson, Sutton, Tautai, Tomkins, Williams, Woods.
Hull FC (from): Shaul, Faraimo, Tuimavave, Griffin, Talanoa, Taylor, Houghton, Connor, Abdull, Washbrook, Fash, Litten, Paea, Lane, Downs, Matongo, Scott, Harris, Bienek.