Salford City Reds' Australian forward Shannan McPherson is unavailable because of medial ligament damage.
Forward Vinnie Anderson will be out for at least six weeks after undergoing surgery on an elbow injury.
Leeds coach Brian McDermott names the same 17 players who defeated Catalan Dragons in Super League last Friday.
Hooker Paul McShane and prop Brad Singleton join the squad and teenager Singleton has made one appearance this season, against London Broncos.
Brian McDermott says on Radio Leeds "It's Super League opposition so there's continuity, we've played them already this season. It's a blessing in disguise because it means we know we have to play well or we'll get beat.
"As I've said before I'd prefer to play a side from our division.
"They play with a structured attack. You might know what they're going to do but it's not always that easy to stop it.
"We had a comfortable day there earlier this season, I don't see it being like that again."
Salford (from): Patten, Broughton, Gleeson, Moon, Williams, Holdsworth, Smith, Jewitt, Godwin, Neal, Ashurst, Adamson, Wild, Sidlow, Paleaaesina, Nero, Howarth, Gibson, James.
Leeds (from): Webb, Jones-Bishop, Hardaker, Hall, McGuire, Leuluai, McShane, Peacock, Ablett, Sinfield, L. Smith, Delaney, Bailey, Kirke, Clarkson, Griffin, Moore, Singleton, Lunt.